Treatment procedures

This part of the website contains medical information pertaining to the mode of administration for Spinraza and other antisense oligonucleotides (ASOs).

Brochure: Lumbar Puncture (in Norwegian)

This brochure contains general information regarding lumbar puncture procedure.

Brochure: Radio-Guided Lumbar Punctures

Scoliotic deformities and orthopedic interventions can make injections via lumbar puncture difficult. This brochure was developed by an experienced cross-functional team at the Hospital Raymond-Poincaré in France. The intention is to share this guideline and best practice for radio-guided lumbar punctures in complex spines. The brochure should only be regarded as a supplement to local guidelines. The assessment and final decision for an individual patient is the responsibility of the treating physician. Please refer to your local guidelines when evaluating the most appropriate medical practices.

Movies: Radio-Guided Lumbar Punctures

SMA TYPE II WITH GROWTH RODS, Dr ADRIEN FELTER

In this movie, Dr. Adrien Felter from the Hospital Raymond-Poincare of Garches, demonstrates a radio-guided intrathecal injection in a type 2 SMA patient with growth rods.
Biogen-42598 - June 2023

SMA TYPE III WITH ARTHRODESIS, Dr BENJAMIN DORÉ

In this movie, Dr. Benjamin Doré from the Hospital Raymond-Poincare of Garches, demonstrates a radio-guided intrathecal injection in a type 3 SMA patient with arthrodesis.
Biogen-42602 - June 2023

SMA TYPE II WITH GROWTH RODS AND NIGHT NIV, Dr BENJAMIN DORÉ

In this movie, Dr. Benjamin Doré from the Hospital Raymond-Poincare of Garches, demonstrates a radio-guided intrathecal injection in a type 2 SMA patient with growth rods and night non-invasive ventilation (NIV).
Biogen-42599 - June 2023

SMA TYPE I WITH TRACHEOSTOMY, Dr ADRIEN FELTER

In this movie, Dr. Adrien Felter from the Hospital Raymond-Poincare of Garches, demonstrates a radio-guided intrathecal injection in a type 1 SMA patient with tracheostomy and instrumentation without transplant.
Biogen-42601 - June 2023

Movies: "SEE IT" - A webinar on complex intrathecal administration

The evolving landscape of SMA, through challenges and solutions – Katia Patanella

Techniques to support intrathecal drug administration: In this video you hear about the latest publications from teen and adult cohorts supporting the use of nusinersen in SMA patients.
Biogen-238040 - April 2024

Eyes on me, please! – Ultrasound for IT injection – Bruno Zanfini

Techniques to support intrathecal drug administration: In this video you get acquainted with the growing evidence of successful ultrasound guided lumbar puncures.
Biogen-238112 - April 2024

Experience with CT guided drug administration and 3D spine modelling – Marek Mechl

Techniques to support intrathecal drug administration: In this video you will familiarize yourself with computed tomography guided lumbar punctures and the use of 3D spine modelling.
Biogen-238698 - April 2024

Fluoroscopy-guided intrathecal therapy with nusinersen – tips and tricks – Jaime Pamplona

Techniques to support intrathecal drug administration: In this video you learn how the use of fluoroscopy can support intrathecal drug administration.
Biogen-238446 - April 2024